What is Abilify?

Abilify is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).

Abilify may also be used for purposes other than those listed in this medication guide.

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What is the most important information I should know about Abilify?

Abilify is not for use in psychotic conditions that are related to dementia. Abilify has caused fatal heart attack and stroke in older adults with dementia-related conditions. Stop using Abilify and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance. Abilify can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which can increase some of the side effects of Abilify.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by Abilify.

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Abilify.

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How should I take Abilify?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Do not take Abilify for longer than 6 weeks unless your doctor has told you to. Take each dose with a full glass of water.

Abilify can be taken with or without food.

Abilify is usually taken once a day. Follow your doctor 's instructions.

Measure the liquid form of Abilify with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

To take Abilify orally disintegrating tablets (Abilify Discmelt):

  • Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

  • Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

  • Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

  • Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.

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What other drugs will affect Abilify?

Before taking Abilify, tell your doctor if you are taking any of the following medicines:

  • a medication to treat high blood pressure or a heart condition;

  • carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin);

  • rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane, Rifater);

  • ketoconazole (Nizoral), itraconazole (Sporanox);

  • quinidine (Cardioquin, Quinaglute); or

  • fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil).

If you are using any of these drugs, you may not be able to use Abilify, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect Abilify. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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